Somatic mutations related to lobular breast cancer

Gene-level and variant-level somatic mutations related to lobular subtype

Subjects

581

Features

492

Cross-sectional study: Somatic mutations from the METABRIC breast cancer dataset were assessed to find variants that best classify/distinguish between lobular and ductal (no specified type) breast carcinoma. This is early research for the application of this method to genetic variant data.

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Pereira, B., Chin, SF., Rueda, O. et al. The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes. Nat Commun 7, 11479 (2016). https://doi.org/10.1038/ncomms11479