Analyst: Jennifer Fouquier


EXPLANA Description and Analysis Summary


EXPLANA Description

EXPLANA uses established machine-learning methods combined with innovative techniques to identify the most relevant features, from a variety of input features, that correlate with a response variable.

Input features and response variables can be numerical, categorical, or from non-normal data distributions. The relationships between selected features and the response can be linear or complex, non-linear relationships.

For longitudinal datasets, changes in features for each study identifier, often subjects, are calculated using different reference points to obtain delta datasets (First, Previous and Pairwise delta datasets). This is important because features in longitudinal studies can carry varying degrees of importance between models built using different reference points. EXPLANA automates feature selection from several models built using these datasets. This report was generated to textually and graphically summarize exploratory analysis and aid hypothesis generation.

Please ensure you understand the workflow, parameters/decisions, and that the percent variation explained (using out-of-bag (OOB) scores) is adequate for your purposes.

When you are using data without prior hypotheses, you are performing exploratory analysis and should make this clear when communicating results.


Response Variable: grade

Analysis Notes:


Methods

Feel free to use the following text, including citation information, for use in methods to ensure reproducibility:

EXPLANA was used for exploratory analysis to identify important features related to the response variable, grade.

A random effect of study_id was used to adjust for non-independence (repeated measurements) if needed. There were 5000 trees used per Random Forest model with a max feature fraction of 0.025 of the input features for each split per decision tree in the forest. If mixed effects Random Forests were needed, 1 iterations were performed. BorutaSHAP was used to find features that perform repeatedly better than shuffled versions of all input features. Features were considered important if they performed better than 95% of the SHAP importance score of the best shuffled feature using 100 trials, p=0.05. Categorical variables were binary encoded and low occuring categorical values were not removed.

These methods are from an EXPLANA feature selection report (version: 2025.05.09) created on 2026-08-22. Additional information can be found at https://github.com/JTFouquier/explana/.


Config File

analyst: Jennifer Fouquier
response_var: grade
include_time: 'no'
random_effect: study_id
sample_id: sample_id
timepoint: timepoint
out: workflow-results/EXPLANA-pancreatic-cancer-somascan-grade/
iterations: '1'
n_estimators: '5000'
max_features: '0.025'
borutashap_trials: '100'
borutashap_threshold: '95'
borutashap_p: '0.05'
analyze_original: 'yes'
analyze_first: 'no'
analyze_previous: 'no'
analyze_pairwise: 'no'
absolute_values: 'no'
include_reference_values: 'no'
analysis_notes: ''
enc_percent_threshold: '0'
distance_matrices: list()
df_mod: ''
delta_df_mod: |
  delta_df <- delta_df
input_datasets:
  metadata:
    file_path: /Users/jenniferfouquier/repos/snakemake-merf/data/pancreatic-somascan/GSE119483_series_matrix_modified.txt
    df_mod: ''
    dim_method: ''
    dim_param_dict:
      method: none

Results Summary

Selected Features by Dataset

Data Original First Previous Pairwise
% Variance Explained 3.5% (45.5%) NA NA NA
N Trees 5000 NA NA NA
Feature fraction/split 0.025 NA NA NA
Max Depth 7 NA NA NA
MERF Iters. NA NA NA NA
BorutaSHAP Trials 100 NA NA NA
BorutaSHAP Threshold 95 NA NA NA
P-value 0.05 NA NA NA
N Study IDs 30 NA NA NA
N Samples 30 NA NA NA
Input Features 1297 NA NA NA
Accepted Features 81 NA NA NA
Tentative Features 37 NA NA NA
Rejected Features 1179 NA NA NA
Model Type (Pass/Fail) RF PASS; Boruta PASS Not performed Not performed Not performed

Selected feature ranks from models built using Original and, for longitudinal analyses, First, Previous and Pairwise delta datasets. Selected features are shown in black and labeled with feature rank. For true/positive instances of categorical variables (indicated with “ENC” after encoding), average impact on response is shown after the rank. For numerical features, impact is not shown because the feature relationship to response can be complex, requiring further post-hoc tests or inspection of SHAP dependence plots for additional insight. Empty grey boxes indicate features included in the model for a dataset, but not selected. Long feature names may be truncated and indicated with ellipses. A comprehensive list of input features can be found in model details below.


Original Dataset


⇨ Open File Directory

Model Summary

Data Original
Model Type (Pass/Fail) RF PASS; Boruta PASS
% Variance Explained 3.5% (45.5%)
N Trees 5000
Feature fraction/split 0.025
Max Depth 7
MERF Iters. NA
BorutaSHAP Trials 100
BorutaSHAP Threshold 95
P-value 0.05
N Study IDs 30
N Samples 30
Input Features 1297
Accepted Features 81
Tentative Features 37
Rejected Features 1179

SHAP summary beeswarm plots of feature influence on the machine learning prediction of response values. Each point represents one sample, and the horizontal position indicates impact on the response as indicated on the x-axis. Points to the left indicate a negative impact, and points to the right indicate a positive impact. The colors represent the selected feature values, where red is larger and blue is smaller. For binary encoded features (‘ENC’) red is yes[1] and blue is no[0]. SHAP is generally an improvement upon other importance scores because it provides information about both rank (how helpful the feature was compared to other features [y-axis]) and impact (a positive or negative impact on response values [x-axis]). If multiple figures are shown, scales may vary with a maximum of ten features per plot.

Selected Features

important_features decoded_features feature_importance_vals
SL004783.P80511.S100A12 SL004783.P80511.S100A12 0.0086
SL004867.P07451.CA3 SL004867.P07451.CA3 0.0083
SL007207.P35443.THBS4 SL007207.P35443.THBS4 0.0079
SL007453.Q15759.MAPK11 SL007453.Q15759.MAPK11 0.0068
SL000310.P00736.C1R SL000310.P00736.C1R 0.0068
SL004557.P13987.CD59 SL004557.P13987.CD59 0.0060
SL008178.Q07507.DPT SL008178.Q07507.DPT 0.0056
SL008904.Q9Y5Y7.LYVE1 SL008904.Q9Y5Y7.LYVE1 0.0055
SL006544.Q15582.TGFBI SL006544.Q15582.TGFBI 0.0055
SL001796.P05164.MPO SL001796.P05164.MPO 0.0054
SL004359.P20783.NTF3 SL004359.P20783.NTF3 0.0054
SL006705.Q99471.PFDN5 SL006705.Q99471.PFDN5 0.0054
SL003187.O00626.CCL22 SL003187.O00626.CCL22 0.0052
SL003197.O15444.CCL25 SL003197.O15444.CCL25 0.0051
SL001777.P01034.CST3 SL001777.P01034.CST3 0.0051
SL006830.Q9BXR6.CFHR5 SL006830.Q9BXR6.CFHR5 0.0050
SL005572.P06396.GSN SL005572.P06396.GSN 0.0050
SL000460.P01880.IGHD IGK@ IGL@ SL000460.P01880.IGHD IGK@ IGL@ 0.0049
SL000027.P35354.PTGS2 SL000027.P35354.PTGS2 0.0049
SL000441.P14210.HGF SL000441.P14210.HGF 0.0048
SL010348.P02751.FN1 SL010348.P02751.FN1 0.0047
SL002621.P21741.MDK SL002621.P21741.MDK 0.0047
SL004180.P28908.TNFRSF8 SL004180.P28908.TNFRSF8 0.0047
SL000408.P01588.EPO SL000408.P01588.EPO 0.0047
SL004120.Q16832.DDR2 SL004120.Q16832.DDR2 0.0046
SL014735.P20839.IMPDH1 SL014735.P20839.IMPDH1 0.0045
SL004672.Q02223.TNFRSF17 SL004672.Q02223.TNFRSF17 0.0045
SL005263.P30533.LRPAP1 SL005263.P30533.LRPAP1 0.0045
SL004489.O00206.TLR4 SL004489.O00206.TLR4 0.0043
SL001938.P08476.INHBA SL001938.P08476.INHBA 0.0043
SL005358.P30086.PEBP1 SL005358.P30086.PEBP1 0.0043
SL004843.O43921.EFNA2 SL004843.O43921.EFNA2 0.0043
SL004296.P00568.AK1 SL004296.P00568.AK1 0.0042
SL007336.Q01105.SET SL007336.Q01105.SET 0.0042
SL012457.P58417.NXPH1 SL012457.P58417.NXPH1 0.0042
SL000022.P02671 P02675 P02679.FGA FGB FGG SL000022.P02671 P02675 P02679.FGA FGB FGG 0.0042
SL004363.Q9Y240.CLEC11A SL004363.Q9Y240.CLEC11A 0.0041
SL000164.P02144.MB SL000164.P02144.MB 0.0041
SL005430.Q8WVN6.SECTM1 SL005430.Q8WVN6.SECTM1 0.0041
SL000836.P69905, P68871.HBA1 HBB SL000836.P69905, P68871.HBA1 HBB 0.0041
SL000403.P39060.COL18A1 SL000403.P39060.COL18A1 0.0041
SL007358.Q04759.PRKCQ SL007358.Q04759.PRKCQ 0.0041
SL012538.Q49AH0.CDNF SL012538.Q49AH0.CDNF 0.0040
SL010450.P09326.CD48 SL010450.P09326.CD48 0.0040
SL010349.P02751.FN1 SL010349.P02751.FN1 0.0040
SL008631.Q02487.DSC2 SL008631.Q02487.DSC2 0.0040
SL005256.P16403.HIST1H1C SL005256.P16403.HIST1H1C 0.0040
SL002704.P21246.PTN SL002704.P21246.PTN 0.0039
SL004858.P56159.GFRA1 SL004858.P56159.GFRA1 0.0039
SL003770.Q8N474.SFRP1 SL003770.Q8N474.SFRP1 0.0038
SL012168.Q9HAP6.LIN7B SL012168.Q9HAP6.LIN7B 0.0038
SL003733.Q9NR28.DIABLO SL003733.Q9NR28.DIABLO 0.0038
SL004008.P24158.PRTN3 SL004008.P24158.PRTN3 0.0038
SL004939.P18031.PTPN1 SL004939.P18031.PTPN1 0.0038
SL004351.Q9H293.IL25 SL004351.Q9H293.IL25 0.0038
SL000645.P09238.MMP10 SL000645.P09238.MMP10 0.0038
SL009400.Q9BU40.CHRDL1 SL009400.Q9BU40.CHRDL1 0.0038
SL019096.Q8N2W9.PIAS4 SL019096.Q8N2W9.PIAS4 0.0037
SL000485.P15248.IL9 SL000485.P15248.IL9 0.0037
SL011073.Q9NQW7.XPNPEP1 SL011073.Q9NQW7.XPNPEP1 0.0037
SL003738.P33681.CD80 SL003738.P33681.CD80 0.0037
SL008639.P22304.IDS SL008639.P22304.IDS 0.0036
SL000498.P41159.LEP SL000498.P41159.LEP 0.0036
SL000306.P16860.NPPB SL000306.P16860.NPPB 0.0036
SL003672.P08294.SOD3 SL003672.P08294.SOD3 0.0036
SL000426.P02751.FN1 SL000426.P02751.FN1 0.0035
SL000525.P09237.MMP7 SL000525.P09237.MMP7 0.0035
SL000461.P01854.IGHE IGK@ IGL@ SL000461.P01854.IGHE IGK@ IGL@ 0.0035
SL005228.Q9BZM5.ULBP2 SL005228.Q9BZM5.ULBP2 0.0034
SL000087.P05231.IL6 SL000087.P05231.IL6 0.0034
SL004342.P55075.FGF8 SL004342.P55075.FGF8 0.0034
SL008504.P15586.GNS SL008504.P15586.GNS 0.0033
SL010495.P24941 P20248.CDK2 CCNA2 SL010495.P24941 P20248.CDK2 CCNA2 0.0033
SL000524.P08254.MMP3 SL000524.P08254.MMP3 0.0032
SL007237.P45985.MAP2K4 SL007237.P45985.MAP2K4 0.0032
SL016548.Q13131 Q9Y478 P54619.PRKAA1 PRKAB1 PRKAG1 SL016548.Q13131 Q9Y478 P54619.PRKAA1 PRKAB1 PRKAG1 0.0032
SL004140.P52798.EFNA4 SL004140.P52798.EFNA4 0.0032
SL004742.P43652.AFM SL004742.P43652.AFM 0.0031
SL002542.P01116.KRAS SL002542.P01116.KRAS 0.0030
SL000057.P04183.TK1 SL000057.P04183.TK1 0.0030
SL004438.Q15828.CST6 SL004438.Q15828.CST6 0.0029

Feature Stats

important_features feature_importance_vals mean std min 25% 50% 75% max
SL004783.P80511.S100A12 0.0086 715.671 359.157 311.910 477.024 650.465 880.821 1811.060
SL004867.P07451.CA3 0.0083 4184.499 4118.548 679.749 1939.644 2906.406 5018.063 20443.365
SL007207.P35443.THBS4 0.0079 351.086 143.929 111.923 265.367 313.587 406.416 669.998
SL007453.Q15759.MAPK11 0.0068 430.305 248.148 236.112 292.788 354.156 407.708 1319.130
SL000310.P00736.C1R 0.0068 2491.258 1421.917 399.856 1203.551 2431.734 3625.020 5563.235
SL004557.P13987.CD59 0.0060 1149.379 248.695 729.258 976.892 1100.076 1331.363 1825.865
SL008178.Q07507.DPT 0.0056 3208.055 1192.236 986.533 2413.245 3245.640 4013.717 5597.498
SL008904.Q9Y5Y7.LYVE1 0.0055 237.160 81.961 130.758 180.542 217.204 276.644 526.316
SL006544.Q15582.TGFBI 0.0055 34288.915 10901.313 13380.544 26723.827 35450.516 42155.235 57481.065
SL001796.P05164.MPO 0.0054 17882.678 6643.441 9518.895 13704.262 16822.113 19267.928 34335.070
SL004359.P20783.NTF3 0.0054 307.148 54.613 215.377 271.228 303.376 345.135 493.919
SL006705.Q99471.PFDN5 0.0054 346.634 97.312 185.607 301.605 346.286 390.741 581.960
SL003187.O00626.CCL22 0.0052 777.490 307.067 294.617 525.869 780.566 980.367 1482.702
SL003197.O15444.CCL25 0.0051 1846.164 1074.996 190.495 993.469 1431.983 2738.834 3886.360
SL001777.P01034.CST3 0.0051 1896.661 569.173 1234.119 1410.502 1786.237 2241.601 3435.993
SL006830.Q9BXR6.CFHR5 0.0050 1146.374 416.801 634.156 856.319 1058.609 1282.387 2244.991
SL005572.P06396.GSN 0.0050 902.491 232.590 370.805 784.303 888.485 1072.081 1344.430
SL000460.P01880.IGHD IGK@ IGL@ 0.0049 6302.373 14117.651 138.430 763.083 1943.916 6906.771 77454.884
SL000027.P35354.PTGS2 0.0049 417.647 74.748 334.751 372.494 390.584 439.656 681.605
SL000441.P14210.HGF 0.0048 3234.482 6044.455 1045.886 1246.728 1636.678 2571.647 33729.051
SL010348.P02751.FN1 0.0047 75094.864 20397.525 40329.435 55117.701 79798.433 89633.868 114268.900
SL002621.P21741.MDK 0.0047 35368.410 42507.742 2758.833 13489.457 19261.155 29880.842 182530.677
SL004180.P28908.TNFRSF8 0.0047 1039.769 479.284 517.065 693.830 991.991 1224.917 2899.081
SL000408.P01588.EPO 0.0047 1644.212 1395.032 299.595 747.152 1321.173 1903.960 6558.056
SL004120.Q16832.DDR2 0.0046 1371.476 372.704 1052.170 1156.353 1282.364 1428.248 2873.760
SL014735.P20839.IMPDH1 0.0045 1394.174 556.947 580.056 931.104 1372.536 1521.859 2836.347
SL004672.Q02223.TNFRSF17 0.0045 5176.816 1461.888 2823.949 4075.978 5142.265 6242.267 8399.907
SL005263.P30533.LRPAP1 0.0045 832.395 291.202 520.247 625.658 788.906 909.307 1917.751
SL004489.O00206.TLR4 0.0043 586.099 1312.024 172.693 220.758 269.535 411.497 7451.665
SL001938.P08476.INHBA 0.0043 5979.241 4018.047 393.726 4290.439 5670.645 7347.387 20963.907
SL005358.P30086.PEBP1 0.0043 4656.539 3438.004 1477.340 2728.863 3603.799 4500.753 15761.221
SL004843.O43921.EFNA2 0.0043 829.092 179.307 515.635 695.911 812.771 945.510 1371.505
SL004296.P00568.AK1 0.0042 29191.090 34875.636 8632.684 11539.930 13109.672 23919.581 137409.216
SL007336.Q01105.SET 0.0042 490.283 102.182 349.053 423.056 484.427 527.519 747.263
SL012457.P58417.NXPH1 0.0042 7181.478 3759.723 2748.263 4347.130 6498.014 9098.422 19375.267
SL000022.P02671 P02675 P02679.FGA FGB FGG 0.0042 10505.914 2824.245 6116.102 8842.709 10018.201 12809.401 16847.891
SL004363.Q9Y240.CLEC11A 0.0041 3572.621 1619.170 1796.907 2384.638 3180.416 4128.067 9651.179
SL000164.P02144.MB 0.0041 961.181 417.563 365.681 670.394 878.622 1135.291 2131.536
SL005430.Q8WVN6.SECTM1 0.0041 1849.450 521.179 1104.737 1501.606 1706.674 2068.539 3071.840
SL000836.P69905, P68871.HBA1 HBB 0.0041 11377.102 37429.435 327.877 674.275 1040.947 1869.440 163970.916
SL000403.P39060.COL18A1 0.0041 68599.388 15564.514 41851.395 57481.065 66776.307 79798.433 98755.881
SL007358.Q04759.PRKCQ 0.0041 1811.569 929.477 847.416 1228.086 1647.933 1898.869 4767.672
SL012538.Q49AH0.CDNF 0.0040 2316.369 660.629 1096.809 1907.096 2215.763 2846.252 3717.584
SL010450.P09326.CD48 0.0040 607.622 167.297 360.784 505.386 625.274 684.465 1167.370
SL010349.P02751.FN1 0.0040 2404.631 1107.322 847.416 1582.794 2304.128 2858.693 5505.400
SL008631.Q02487.DSC2 0.0040 2823.060 954.738 1363.181 2141.760 2880.093 3165.801 5468.456
SL005256.P16403.HIST1H1C 0.0040 274.326 140.545 122.816 184.634 229.824 318.033 756.530
SL002704.P21246.PTN 0.0039 3727.045 12180.571 513.798 891.355 1135.279 1634.808 67823.900
SL004858.P56159.GFRA1 0.0039 3033.441 7260.062 363.826 1329.269 1466.863 1859.595 41058.507
SL003770.Q8N474.SFRP1 0.0038 9986.383 29360.593 431.381 2799.175 4061.915 5557.912 163970.916
SL012168.Q9HAP6.LIN7B 0.0038 254.974 33.963 208.886 234.405 253.136 265.998 397.658
SL003733.Q9NR28.DIABLO 0.0038 4504.977 3335.261 2600.123 3342.202 3924.867 4307.609 21465.337
SL004008.P24158.PRTN3 0.0038 4250.176 2244.576 1496.726 2478.446 3756.445 4987.753 9857.265
SL004939.P18031.PTPN1 0.0038 1299.148 369.428 873.333 983.769 1235.730 1469.115 2288.888
SL004351.Q9H293.IL25 0.0038 329.997 84.913 215.377 277.977 321.592 356.297 591.972
SL000645.P09238.MMP10 0.0038 1301.757 984.027 341.537 774.330 952.085 1605.778 4923.256
SL009400.Q9BU40.CHRDL1 0.0038 2642.513 1584.862 1373.142 1839.700 2410.365 2953.486 10182.626
SL019096.Q8N2W9.PIAS4 0.0037 830.201 221.968 483.265 686.308 781.633 1007.526 1357.740
SL000485.P15248.IL9 0.0037 326.348 398.087 138.430 192.041 232.051 311.142 2386.965
SL011073.Q9NQW7.XPNPEP1 0.0037 5521.247 3168.381 685.419 3982.793 5060.999 6932.860 12380.977
SL003738.P33681.CD80 0.0037 491.591 246.907 314.577 385.717 435.765 485.518 1379.542
SL008639.P22304.IDS 0.0036 2521.891 1215.731 520.247 1826.212 2431.112 3133.659 5846.677
SL000498.P41159.LEP 0.0036 6914.616 6571.476 667.819 2045.477 5077.453 9269.494 29274.721
SL000306.P16860.NPPB 0.0036 421.223 197.842 273.135 322.572 377.131 434.424 1332.051
SL003672.P08294.SOD3 0.0036 880.332 1259.516 243.105 344.410 459.462 583.687 5622.474
SL000426.P02751.FN1 0.0035 13586.380 7318.139 2119.442 8588.760 11743.079 18632.560 29674.672
SL000525.P09237.MMP7 0.0035 1977.690 1144.679 403.107 1428.256 1737.990 2221.983 5906.542
SL000461.P01854.IGHE IGK@ IGL@ 0.0035 7908.568 12103.871 199.849 1083.008 3315.148 7003.731 50357.616
SL005228.Q9BZM5.ULBP2 0.0034 473.505 386.759 250.616 293.805 344.753 429.426 1830.988
SL000087.P05231.IL6 0.0034 630.779 538.458 309.384 367.217 427.805 575.310 2899.081
SL004342.P55075.FGF8 0.0034 600.588 190.459 377.077 493.526 540.381 625.553 1167.370
SL008504.P15586.GNS 0.0033 2171.524 812.511 660.230 1615.306 2202.871 2529.334 4205.260
SL010495.P24941 P20248.CDK2 CCNA2 0.0033 292.848 204.268 179.063 216.677 234.248 267.580 1141.172
SL000524.P08254.MMP3 0.0032 840.904 832.727 241.784 326.704 610.647 931.650 4245.747
SL007237.P45985.MAP2K4 0.0032 49547.635 22098.095 4245.747 34954.195 53847.628 63671.070 94457.686
SL016548.Q13131 Q9Y478 P54619.PRKAA1 PRKAB1 PRKAG1 0.0032 299.604 66.915 227.814 257.637 278.167 318.773 483.265
SL004140.P52798.EFNA4 0.0032 1544.449 355.646 1064.702 1286.448 1447.756 1757.097 2328.205
SL004742.P43652.AFM 0.0031 22548.227 7150.959 3139.528 18587.716 24831.798 27673.287 32610.065
SL002542.P01116.KRAS 0.0030 906.610 336.001 527.826 701.785 806.521 1072.081 2068.940
SL000057.P04183.TK1 0.0030 467.463 337.878 246.293 340.462 387.431 467.717 2142.660
SL004438.Q15828.CST6 0.0029 4661.441 1938.515 1939.644 3308.006 4353.935 5913.231 9052.898

Input Features

input_features was_selected
age no
SL000001.P15941.MUC1 no
SL000002.P15692.VEGFA no
SL000003.P03950.ANG no
SL000004.P09038.FGF2 no
SL000007.P03372.ESR1 no
SL000009.P04626.ERBB2 no
SL000011.P02771.AFP no
SL000017.P04275.VWF no
SL000019.P02647.APOA1 no
SL000020.P04114.APOB no
SL000021.P01308.INS no
SL000022.P02671 P02675 P02679.FGA FGB FGG yes
SL000024.P13726.F3 no
SL000027.P35354.PTGS2 yes
SL000038.P13500.CCL2 no
SL000039.P10145.CXCL8 no
SL000045.P17936.IGFBP3 no
SL000047.P05019.IGF1 no
SL000048.P04070.PROC no
SL000049.P07225.PROS1 no
SL000051.P02741.CRP no
SL000052.P45379.TNNT2 no
SL000053.P00750.PLAT no
SL000055.P12830.CDH1 no
SL000057.P04183.TK1 yes
SL000062.P07288.KLK3 no
SL000064.P49862.KLK7 no
SL000070.P51654.GPC3 no
SL000074.P04637.TP53 no
SL000076.P46527.CDKN1B no
SL000084.P01133.EGF no
SL000087.P05231.IL6 yes
SL000088.P61812.TGFB2 no
SL000089.P10600.TGFB3 no
SL000104.P10415.BCL2 no
SL000124.P08253.MMP2 no
SL000125.P01583.IL1A no
SL000130.P14635.CCNB1 no
SL000131.P12004.PCNA no
SL000133.P78556.CCL20 no
SL000134.P08581.MET no
SL000136.P15514.AREG no
SL000137.P35070.BTC no
SL000138.Q99075.HBEGF no
SL000139.O14944.EREG no
SL000142.P04818.TYMS no
SL000145.P27930.IL1R2 no
SL000158.Q04609.FOLH1 no
SL000164.P02144.MB yes
SL000248.P01011.SERPINA3 no
SL000249.P01009.SERPINA1 no
SL000250.P08697.SERPINF2 no
SL000251.P02765.AHSG no
SL000252.P01023.A2M no
SL000254.P02768.ALB no
SL000268.P00747.PLG no
SL000271.P01019.AGT no
SL000272.P01008.SERPINC1 no
SL000276.P02649.APOE no
SL000277.P02649.APOE no
SL000280.P17174.GOT1 no
SL000283.P61769.B2M no
SL000299.P05230.FGF1 no
SL000300.P01189.POMC no
SL000305.P01138.NGF no
SL000306.P16860.NPPB yes
SL000308.P05155.SERPING1 no
SL000309.P02745 P02746 P02747.C1QA C1QB C1QC no
SL000310.P00736.C1R yes
SL000311.P09871.C1S no
SL000312.P01024.C3 no
SL000313.P01024.C3 no
SL000316.P0C0L4, P0C0L5.C4A C4B no
SL000318.P0C0L4 P0C0L5.C4A C4B no
SL000319.P01031.C5 no
SL000320.P01031.C5 no
SL000322.P13671.C6 no
SL000323.P10643.C7 no
SL000324.P07357,P07358,P07360.C8A C8B C8G no
SL000325.P02748.C9 no
SL000337.P07384 P04632.CAPN1 CAPNS1 no
SL000338.P20810.CAST no
SL000339.P00918.CA2 no
SL000342.P04040.CAT no
SL000343.P07858.CTSB no
SL000344.P07339.CTSD no
SL000345.P08311.CTSG no
SL000346.P09668.CTSH no
SL000347.P08185.SERPINA6 no
SL000357.P00740.F9 no
SL000358.P08709.F7 no
SL000360.P00742.F10 no
SL000377.P12277.CKB no
SL000382.P12277 P06732.CKB CKM no
SL000383.P06732.CKM no
SL000384.P16410.CTLA4 no
SL000396.P99999.CYCS no
SL000398.P08684.CYP3A4 no
SL000401.P08246.ELANE no
SL000403.P39060.COL18A1 yes
SL000406.P51671.CCL11 no
SL000408.P01588.EPO yes
SL000409.P27361.MAPK3 no
SL000414.P00751.CFB no
SL000415.P08603.CFH no
SL000420.P02794 P02792.FTH1 FTL no
SL000424.P02671 P02675 P02679.FGA FGB FGG no
SL000426.P02751.FN1 yes
SL000427.P78423.CX3CL1 no
SL000428.P01215, P01225.CGA FSHB no
SL000433.P01275.GCG no
SL000437.P00738.HP no
SL000440.P02790.HPX no
SL000441.P14210.HGF yes
SL000442.P01241.GH1 no
SL000445.P18093.Human-virus no
SL000448.P04792.HSPB1 no
SL000449.P25685.DNAJB1 no
SL000450.P10809.HSPD1 no
SL000451.P0DMV8.HSPA1A no
SL000454.P08238.HSP90AB1 no
SL000455.P05412.JUN no
SL000456.P01024.C3 no
SL000458.P15260.IFNGR1 no
SL000459.P01876 P01877.IGHA1 IGHA2 no
SL000460.P01880.IGHD IGK@ IGL@ yes
SL000461.P01854.IGHE IGK@ IGL@ yes
SL000462.P08833.IGFBP1 no
SL000466.P18065.IGFBP2 no
SL000467.P01857.IGHG1 IGHG2 IGHG3 IGHG4 IGK@ IGL@ no
SL000468.P01871.IGHM IGJ IGK@ IGL@ no
SL000470.P20809.IL11 no
SL000474.Q14005.IL16 no
SL000478.P60568.IL2 no
SL000479.P08700.IL3 no
SL000480.P05112.IL4 no
SL000481.P05113.IL5 no
SL000483.P13232.IL7 no
SL000485.P15248.IL9 yes
SL000493.P07195.LDHB no
SL000496.P02788.LTF no
SL000497.P25391, P07942, P11047.LAMA1 LAMB1 LAMC1 no
SL000498.P41159.LEP yes
SL000506.P01215, P01229.CGA LHB no
SL000507.P01374, Q06643.LTA LTB no
SL000508.P01374, Q06643.LTA LTB no
SL000509.P36941.LTBR no
SL000510.P61626.LYZ no
SL000515.P80075.CCL8 no
SL000516.P80098.CCL7 no
SL000517.Q99616.CCL13 no
SL000519.P10147.CCL3 no
SL000521.P03956.MMP1 no
SL000522.P39900.MMP12 no
SL000523.P45452.MMP13 no
SL000524.P08254.MMP3 yes
SL000525.P09237.MMP7 yes
SL000526.P22894.MMP8 no
SL000527.P14780.MMP9 no
SL000528.P16435.POR no
SL000530.P13725.OSM no
SL000532.P09486.SPARC no
SL000535.P04085.PDGFA no
SL000537.P01127.PDGFB no
SL000539.P06744.GPI no
SL000540.P00747.PLG no
SL000541.P00747.PLG no
SL000542.P08514 P05106.ITGA2B ITGB3 no
SL000545.P03952.KLKB1 no
SL000546.P01236.PRL no
SL000550.P05154.SERPINA5 no
SL000551.P17252.PRKCA no
SL000553.P05771.PRKCB no
SL000554.Q05655.PRKCD no
SL000556.P05129.PRKCG no
SL000557.Q05513.PRKCZ no
SL000558.P00734.F2 no
SL000560.P16109.SELP no
SL000563.P13501.CCL5 no
SL000565.P00797.REN no
SL000566.P02753.RBP4 no
SL000570.P09683.SCT no
SL000572.P0DJI8.SAA1 no
SL000573.P02743.APCS no
SL000581.P00441.SOD1 no
SL000582.O15392.BIRC5 no
SL000584.P01137.TGFB1 no
SL000586.P00734.F2 no
SL000587.P01266.TG no
SL000588.P07202.TPO no
SL000589.P01215 P01222.CGA TSHB no
SL000590.P05543.SERPINA7 no
SL000591.P01033.TIMP1 no
SL000592.P16035.TIMP2 no
SL000597.P01374.LTA no
SL000598.P40225.THPO no
SL000601.P02787.TF no
SL000603.P07477.PRSS1 no
SL000605.P62979.RPS27A no
SL000613.P00749.PLAU no
SL000615.P01282.VIP no
SL000616.P04004.VTN no
SL000617.P24298.GPT no
SL000622.P12259.F5 no
SL000633.P48023.FASLG no
SL000638.P19022.CDH2 no
SL000640.P14543.NID1 no
SL000645.P09238.MMP10 yes
SL000655.P05783.KRT18 no
SL000658.P54826.GAS1 no
SL000668.P16671.CD36 no
SL000670.Q16772.GSTA3 no
SL000674.P19883.FST no
SL000678.P22749.GNLY no
SL000695.P80188.LCN2 no
SL000836.P69905, P68871.HBA1 HBB yes
SL001691.P21781.FGF7 no
SL001713.Q16552.IL17A no
SL001716.P29459, P29460.IL12A IL12B no
SL001717.P22301.IL10 no
SL001718.P35225.IL13 no
SL001720.P19320.VCAM1 no
SL001721.P16284.PECAM1 no
SL001726.P04141.CSF2 no
SL001728.P16234.PDGFRA no
SL001729.P09919.CSF3 no
SL001731.P09104.ENO2 no
SL001737.P31947.SFN no
SL001753.Q9BZZ2.SIGLEC1 no
SL001761.P19429.TNNI3 no
SL001766.P01215,P01233.CGA CGB no
SL001774.P05413.FABP3 no
SL001777.P01034.CST3 yes
SL001791.P02818.BGLAP no
SL001795.P01584.IL1B no
SL001796.P05164.MPO yes
SL001797.Q92876.KLK6 no
SL001800.P20333.TNFRSF1B no
SL001802.P01579.IFNG no
SL001815.P04179.SOD2 no
SL001880.P01574.IFNB1 no
SL001888.P03973.SLPI no
SL001890.P09758.TACSTD2 no
SL001896.P10909.CLU no
SL001897.O43291.SPINT2 no
SL001902.P50895.BCAM no
SL001905.Q13421.MSLN no
SL001938.P08476.INHBA yes
SL001943.P08887.IL6R no
SL001945.P16581.SELE no
SL001947.Q16674.MIA no
SL001973.O75556.SCGB2A1 no
SL001990.P18510.IL1RN no
SL001992.P19438.TNFRSF1A no
SL001995.Q15389.ANGPT1 no
SL001996.O15123.ANGPT2 no
SL001997.P14778.IL1R1 no
SL001998.P10646.TFPI no
SL001999.Q00987.MDM2 no
SL002036.P22455.FGFR4 no
SL002071.P07492.GRP no
SL002075.P01563.IFNA2 no
SL002077.P05186.ALPL no
SL002078.P37173.TGFBR2 no
SL002081.P33151.CDH5 no
SL002086.O75636.FCN3 no
SL002093.P0C0S5.H2AFZ no
SL002505.P01160.NPPA no
SL002506.Q03405.PLAUR no
SL002508.O95998.IL18BP no
SL002517.P01375.TNF no
SL002519.P21860.ERBB3 no
SL002522.P06400.RB1 no
SL002524.P01730.CD4 no
SL002525.P06681.C2 no
SL002528.P14555.PLA2G2A no
SL002539.O00300.TNFRSF11B no
SL002541.O14788.TNFSF11 no
SL002542.P01116.KRAS yes
SL002561.P12272.PTHLH no
SL002565.P01106.MYC no
SL002602.Q03403.TFF2 no
SL002621.P21741.MDK yes
SL002640.P49763.PGF no
SL002644.P00533.EGFR no
SL002646.P50281.MMP14 no
SL002650.P14618.PKM2 no
SL002654.P29317.EPHA2 no
SL002655.P29279.CTGF no
SL002662.P03951.F11 no
SL002684.P09603.CSF1 no
SL002688.P10451.SPP1 no
SL002695.Q96KP4.CNDP2 no
SL002702.P11309.PIM1 no
SL002704.P21246.PTN yes
SL002705.P07996.THBS1 no
SL002706.P06734.FCER2 no
SL002722.P28907.CD38 no
SL002731.P25445.FAS no
SL002755.Q13219.PAPPA no
SL002756.P61978.HNRNPK no
SL002762.P10645.CHGA no
SL002763.Q9UBX7.KLK11 no
SL002782.P35318.ADM no
SL002783.Q16619.CTF1 no
SL002785.P16860.NPPB no
SL002792.P25098.ADRBK1 no
SL002803.P09936.UCHL1 no
SL002823.P14151.SELL no
SL002922.P05362.ICAM1 no
SL003043.P35625.TIMP3 no
SL003060.P11362.FGFR1 no
SL003066.P36955.SERPINF1 no
SL003080.P14174.MIF no
SL003104.O00175.CCL24 no
SL003166.Q13740.ALCAM no
SL003167.O43927.CXCL13 no
SL003168.Q9Y4X3.CCL27 no
SL003169.P42830.CXCL5 no
SL003170.Q9Y258.CCL26 no
SL003171.P08620.FGF4 no
SL003172.P80162.CXCL6 no
SL003173.P09341.CXCL1 no
SL003176.P22362.CCL1 no
SL003177.P13598.ICAM2 no
SL003178.P32942.ICAM3 no
SL003179.P56199, P05556.ITGA1 ITGB1 no
SL003182.P06756, P18084.ITGAV ITGB5 no
SL003183.P02778.CXCL10 no
SL003184.P48357.LEPR no
SL003186.P47992.XCL1 no
SL003187.O00626.CCL22 yes
SL003188.Q07325.CXCL9 no
SL003189.Q99731.CCL19 no
SL003190.Q16663.CCL15 no
SL003191.P02775.PPBP no
SL003192.P27918.CFP no
SL003193.O00585.CCL21 no
SL003196.Q92583.CCL17 no
SL003197.O15444.CCL25 yes
SL003198.P24821.TNC no
SL003199.P35590.TIE1 no
SL003200.Q02763.TEK no
SL003201.P35968.KDR no
SL003220.P01024.C3 no
SL003280.P09429.HMGB1 no
SL003300.O15467.CCL16 no
SL003301.P55773.CCL23 no
SL003302.P55773.CCL23 no
SL003303.Q9NRJ3.CCL28 no
SL003304.P08069.IGF1R no
SL003305.P01589.IL2RA no
SL003307.P31785.IL2RG no
SL003308.P24394.IL4R no
SL003309.P18428.LBP no
SL003310.P15692.VEGFA no
SL003320.O43915.FIGF no
SL003322.P35916.FLT4 no
SL003323.P55774.CCL18 no
SL003324.P00742.F10 no
SL003326.O14625.CXCL11 no
SL003327.P00746.CFD no
SL003328.P05156.CFI no
SL003329.Q16627.CCL14 no
SL003331.P51512.MMP16 no
SL003332.Q9ULZ9.MMP17 no
SL003334.Q12904.AIMP1 no
SL003340.P36222.CHI3L1 no
SL003341.P02679.FGG no
SL003349.Q16665.HIF1A no
SL003362.P01024.C3 no
SL003440.Q13093.PLA2G7 no
SL003461.P01189.POMC no
SL003520.P27797.CALR no
SL003522.P30040.ERP29 no
SL003524.P30101.PDIA3 no
SL003542.Q96KQ7.EHMT2 no
SL003643.P09211.GSTP1 no
SL003646.P67936.TPM4 no
SL003647.P08133.ANXA6 no
SL003648.P50395.GDI2 no
SL003650.P06733.ENO1 no
SL003653.P00558.PGK1 no
SL003655.P29401.TKT no
SL003657.Q08209 P63098.PPP3CA PPP3R1 no
SL003658.O43488.AKR7A2 no
SL003672.P08294.SOD3 yes
SL003674.Q07817.BCL2L1 no
SL003679.P11717.IGF2R no
SL003680.Q15109.AGER no
SL003685.P43490.NAMPT no
SL003687.P15531.NME1 no
SL003690.Q9Y6Q6.TNFRSF11A no
SL003700.Q92934.BAD no
SL003703.Q16548.BCL2A1 no
SL003704.P55957.BID no
SL003710.P42575.CASP2 no
SL003711.P42574.CASP3 no
SL003717.Q92851.CASP10 no
SL003722.P31751.AKT2 no
SL003726.O96017.CHEK2 no
SL003728.Q13489.BIRC3 no
SL003733.Q9NR28.DIABLO yes
SL003735.P41273.TNFSF9 no
SL003738.P33681.CD80 yes
SL003739.O95407.TNFRSF6B no
SL003744.P17931.LGALS3 no
SL003753.P63167.DYNLL1 no
SL003755.Q07820.MCL1 no
SL003761.P60484.PTEN no
SL003764.P13591.NCAM1 no
SL003770.Q8N474.SFRP1 yes
SL003774.Q92843.BCL2L2 no
SL003785.P04406.GAPDH no
SL003792.P62993.GRB2 no
SL003793.Q02750.MAP2K1 no
SL003800.Q9Y5K2.KLK4 no
SL003803.Q15303.ERBB4 no
SL003848.P08758.ANXA5 no
SL003849.P31371.FGF9 no
SL003862.P29965.CD40LG no
SL003863.Q9Y337.KLK5 no
SL003869.Q99988.GDF15 no
SL003872.P40189.IL6ST no
SL003915.O60259.KLK8 no
SL003916.Q9UKR0.KLK12 no
SL003918.Q9UKR3.KLK13 no
SL003919.Q9P0G3.KLK14 no
SL003930.P15428.HPGD no
SL003951.P23560.BDNF no
SL003970.P01270.PTH no
SL003974.P04070.PROC no
SL003990.P21802.FGFR2 no
SL003993.P22004.BMP6 no
SL003994.P13497.BMP1 no
SL004008.P24158.PRTN3 yes
SL004009.P63000.RAC1 no
SL004010.P10721.KIT no
SL004015.Q96IY4.CPB2 no
SL004016.Q9H2A7.CXCL16 no
SL004060.P42892.ECE1 no
SL004063.P22607.FGFR3 no
SL004064.P04054.PLA2G1B no
SL004066.Q9NZK7.PLA2G2E no
SL004067.O15496.PLA2G10 no
SL004068.P10144.GZMB no
SL004070.P62979.RPS27A no
SL004078.P18075.BMP7 no
SL004080.P36894.BMPR1A no
SL004081.P07585.DCN no
SL004097.P84022.SMAD3 no
SL004101.Q15796.SMAD2 no
SL004118.P13686.ACP5 no
SL004119.Q08345.DDR1 no
SL004120.Q16832.DDR2 yes
SL004125.P06213.INSR no
SL004126.Q07011.TNFRSF9 no
SL004128.P36896.ACVR1B no
SL004131.P42081.CD86 no
SL004133.Q13873.BMPR2 no
SL004136.Q06418.TYRO3 no
SL004137.P21709.EPHA1 no
SL004139.P52797.EFNA3 no
SL004140.P52798.EFNA4 yes
SL004141.P52803.EFNA5 no
SL004142.Q15768.EFNB3 no
SL004143.O00451.GFRA2 no
SL004144.O60609.GFRA3 no
SL004145.Q92956.TNFRSF14 no
SL004146.Q01638.IL1RL1 no
SL004147.Q08334.IL10RB no
SL004148.P42701.IL12RB1 no
SL004149.P78552.IL13RA1 no
SL004151.Q13261.IL15RA no
SL004152.Q13478.IL18R1 no
SL004153.P07333.CSF1R no
SL004154.P32004.L1CAM no
SL004155.P09619.PDGFRB no
SL004156.O00220.TNFRSF10A no
SL004157.O14763.TNFRSF10B no
SL004159.Q9UBN6.TNFRSF10D no
SL004160.Q16620.NTRK2 no
SL004180.P28908.TNFRSF8 yes
SL004182.P39877.PLA2G5 no
SL004183.P22223.CDH3 no
SL004208.P04083.ANXA1 no
SL004209.P07355.ANXA2 no
SL004230.P10636.MAPT no
SL004248.P39905.GDNF no
SL004253.P14061.HSD17B1 no
SL004258.Q15848.ADIPOQ no
SL004260.Q9HD89.RETN no
SL004269.Q9UBU3.GHRL no
SL004271.P14136.GFAP no
SL004296.P00568.AK1 yes
SL004297.Q02297.NRG1 no
SL004298.P12544.GZMA no
SL004299.Q96CA5.BIRC7 no
SL004301.P12956.XRCC6 no
SL004304.Q16623.STX1A no
SL004305.P11387.TOP1 no
SL004306.P63279.UBE2I no
SL004326.Q9UNG2.TNFSF18 no
SL004327.Q9Y275.TNFSF13B no
SL004329.P43026.GDF5 no
SL004330.P20273.CD22 no
SL004331.P26441.CNTF no
SL004332.P58294.PROK1 no
SL004333.O15520.FGF10 no
SL004334.O43320.FGF16 no
SL004335.O60258.FGF17 no
SL004336.O76093.FGF18 no
SL004337.O95750.FGF19 no
SL004338.Q9NP95.FGF20 no
SL004339.P12034.FGF5 no
SL004340.P10767.FGF6 no
SL004342.P55075.FGF8 yes
SL004343.P49771.FLT3LG no
SL004345.O95390.GDF11 no
SL004346.Q9NYY1.IL20 no
SL004347.Q9GZX6.IL22 no
SL004348.Q8IU54.IFNL1 no
SL004349.Q8IZJ0.IFNL2 no
SL004350.Q9UHF5.IL17B no
SL004351.Q9H293.IL25 yes
SL004352.Q96PD4.IL17F no
SL004353.Q8TAD2.IL17D no
SL004354.Q9UHD0.IL19 no
SL004355.P16619.CCL3L1 no
SL004356.Q8NHW4.CCL4L1 no
SL004357.O14793.MSTN no
SL004359.P20783.NTF3 yes
SL004360.P34130.NTF4 no
SL004362.Q9Y240.CLEC11A no
SL004363.Q9Y240.CLEC11A yes
SL004364.O14836.TNFRSF13B no
SL004365.O43508.TNFSF12 no
SL004366.Q9NP84.TNFRSF12A no
SL004367.O94907.DKK1 no
SL004396.P42224.STAT1 no
SL004400.P00740.F9 no
SL004415.Q9BYF1.ACE2 no
SL004438.Q15828.CST6 yes
SL004457.P07093.SERPINE2 no
SL004458.P19957.PI3 no
SL004466.P05546.SERPIND1 no
SL004467.Q9UK55.SERPINA10 no
SL004469.P05067.APP no
SL004475.P17181.IFNAR1 no
SL004477.P06702.S100A9 no
SL004482.P17813.ENG no
SL004484.P35247.SFTPD no
SL004486.P49767.VEGFC no
SL004489.O00206.TLR4 yes
SL004492.O60603.TLR2 no
SL004511.P17213.BPI no
SL004515.O75594.PGLYRP1 no
SL004516.P11226.MBL2 no
SL004536.P81172.HAMP no
SL004556.P08174.CD55 no
SL004557.P13987.CD59 yes
SL004579.P22897.MRC1 no
SL004580.P21757.MSR1 no
SL004588.Q9NPH3.IL1RAP no
SL004589.P20160.AZU1 no
SL004591.Q99062.CSF3R no
SL004594.P48788.TNNI2 no
SL004605.P08865.RPSA no
SL004610.Q14114.LRP8 no
SL004625.O75173.ADAMTS4 no
SL004626.Q9UNA0.ADAMTS5 no
SL004635.P32971.TNFSF8 no
SL004636.P36888.FLT3 no
SL004637.Q04912.MST1R no
SL004639.Q16288.NTRK3 no
SL004642.Q13443.ADAM9 no
SL004643.Q9Y264.ANGPT4 no
SL004644.Q92838.EDA no
SL004645.O43278.SPINT1 no
SL004646.Q6UX15.LAYN no
SL004648.O43557.TNFSF14 no
SL004649.P23510.TNFSF4 no
SL004650.Q92765.FRZB no
SL004652.Q9Y5W5.WIF1 no
SL004654.P20718.GZMH no
SL004660.P21815.IBSP no
SL004661.P16112.ACAN no
SL004668.P02649.APOE no
SL004669.P02649.APOE no
SL004670.Q5T4W7.ARTN no
SL004671.Q96RJ3.TNFRSF13C no
SL004672.Q02223.TNFRSF17 yes
SL004673.P25774.CTSS no
SL004676.P24593.IGFBP5 no
SL004683.Q13253.NOG no
SL004685.O60542.PSPN no
SL004686.O95150.TNFSF15 no
SL004687.Q969D9.TSLP no
SL004689.O95388.WISP1 no
SL004690.O95389.WISP3 no
SL004692.O75462 Q9UBD9.CRLF1 CLCF1 no
SL004697.P03129.Human-virus no
SL004698.P06788.Human-virus no
SL004704.Q86VX2.COMMD7 no
SL004708.P02775.PPBP no
SL004712.P48061.CXCL12 no
SL004714.P42702.LIFR no
SL004716.P45984.MAPK9 no
SL004718.P52292.KPNA2 no
SL004720.P63098.PPP3R1 no
SL004723.Q9BY41.HDAC8 no
SL004724.Q92794.KAT6A no
SL004725.O14929.HAT1 no
SL004726.P48960.CD97 no
SL004733.Q07954.LRP1 no
SL004737.P09493.TPM1 no
SL004739.Q14624.ITIH4 no
SL004742.P43652.AFM yes
SL004747.O95445.APOM no
SL004750.Q9UMR2.DDX19B no
SL004751.P30519.HMOX2 no
SL004752.O95990.FAM107A no
SL004757.Q9NP79.VTA1 no
SL004759.P55010.EIF5 no
SL004760.P68402.PAFAH1B2 no
SL004765.Q16644.MAPKAPK3 no
SL004768.P55008.AIF1 no
SL004771.O14965.AURKA no
SL004781.P41240.CSK no
SL004782.P98066.TNFAIP6 no
SL004783.P80511.S100A12 yes
SL004791.Q93038.TNFRSF25 no
SL004795.Q99714.HSD17B10 no
SL004804.Q8N126.CADM3 no
SL004805.Q9BY67.CADM1 no
SL004811.P37802.TAGLN2 no
SL004812.P60174.TPI1 no
SL004814.Q14019.COTL1 no
SL004815.P31946.YWHAB no
SL004820.P18669.PGAM1 no
SL004821.P26447.S100A4 no
SL004823.P62937.PPIA no
SL004827.P06703.S100A6 no
SL004829.P31151.S100A7 no
SL004837.P08476 P09529.INHBA INHBB no
SL004838.Q08722.CD47 no
SL004843.O43921.EFNA2 yes
SL004844.P54756.EPHA5 no
SL004845.P54760.EPHB4 no
SL004849.Q9NP60.IL1RAPL2 no
SL004850.Q96F46.IL17RA no
SL004851.P37023.ACVRL1 no
SL004852.Q9NZQ7.CD274 no
SL004853.O75144.ICOSLG no
SL004855.Q12860.CNTN1 no
SL004856.Q02413.DSG1 no
SL004857.Q14126.DSG2 no
SL004858.P56159.GFRA1 yes
SL004859.Q9Y5U5.TNFRSF18 no
SL004860.O43464.HTRA2 no
SL004861.O95256.IL18RAP no
SL004862.Q9BQ51.PDCD1LG2 no
SL004863.Q9NS68.TNFRSF19 no
SL004864.P55289.CDH12 no
SL004865.P55285.CDH6 no
SL004866.P00915.CA1 no
SL004867.P07451.CA3 yes
SL004868.P43166.CA7 no
SL004869.Q8N1Q1.CA13 no
SL004871.O75509.TNFRSF21 no
SL004872.Q9UNE0.EDAR no
SL004875.Q9HB29.IL1RL2 no
SL004876.P29622.SERPINA4 no
SL004891.P22626.HNRNPA2B1 no
SL004899.P11142.HSPA8 no
SL004901.P07237.P4HB no
SL004908.P07951.TPM2 no
SL004910.P04075.ALDOA no
SL004914.Q15181.PPA1 no
SL004915.O00299.CLIC1 no
SL004919.Q06830.PRDX1 no
SL004920.P23528.CFL1 no
SL004921.P22392.NME2 no
SL004924.Q15056.EIF4H no
SL004925.O95994.AGR2 no
SL004932.P30044.PRDX5 no
SL004938.Q8N5S9.CAMKK1 no
SL004939.P18031.PTPN1 yes
SL004940.P29350.PTPN6 no
SL004984.P62258.YWHAE no
SL005034.P62826.RAN no
SL005059.Q03167.TGFBR3 no
SL005084.Q15063.POSTN no
SL005087.Q16270.IGFBP7 no
SL005102.P04278.SHBG no
SL005115.Q9HCB6.SPON1 no
SL005152.Q99969.RARRES2 no
SL005153.P26992.CNTFR no
SL005155.P13385.TDGF1 no
SL005156.P41271.NBL1 no
SL005157.Q9NNX6.CD209 no
SL005158.Q9H2X3.CLEC4M no
SL005159.P19235.EPOR no
SL005160.Q96AP7.ESAM no
SL005161.P61328.FGF12 no
SL005164.P05162.LGALS2 no
SL005165.P56470.LGALS4 no
SL005166.P47929.LGALS7 no
SL005167.O00214.LGALS8 no
SL005168.P10912.GHR no
SL005169.Q9UMF0.ICAM5 no
SL005171.P22692.IGFBP4 no
SL005172.P24592.IGFBP6 no
SL005173.Q13651.IL10RA no
SL005174.Q9NRM6.IL17RB no
SL005177.Q9UHA7.IL36A no
SL005178.Q9NZH6.IL37 no
SL005179.Q9NZH7.IL36B no
SL005181.Q9UHF4.IL20RA no
SL005183.Q969J5.IL22RA2 no
SL005184.P29460, Q9NPF7.IL12B IL23A no
SL005185.Q5VWK5.IL23R no
SL005187.P26951.IL3RA no
SL005188.Q01344.IL5RA no
SL005189.P16871.IL7R no
SL005190.Q8NHL6.LILRB1 no
SL005191.Q8N423.LILRB2 no
SL005193.P57087.JAM2 no
SL005194.Q9BX67.JAM3 no
SL005195.P18627.LAG3 no
SL005196.Q13449.LSAMP no
SL005197.Q14108.SCARB2 no
SL005199.Q29983.MICA no
SL005200.Q29980.MICB no
SL005201.P03971.AMH no
SL005202.P26927.MST1 no
SL005204.P26718.KLRK1 no
SL005205.O14931.NCR3 no
SL005206.O95944.NCR2 no
SL005207.O76036.NCR1 no
SL005208.Q9BZR6.RTN4R no
SL005209.Q9UM47.NOTCH3 no
SL005210.Q92823.NRCAM no
SL005212.P16471.PRLR no
SL005213.Q969Z4.RELT no
SL005214.Q9H2E6.SEMA6A no
SL005215.P20138.CD33 no
SL005217.O43699.SIGLEC6 no
SL005218.Q9Y286.SIGLEC7 no
SL005219.Q9Y336.SIGLEC9 no
SL005220.Q15465.SHH no
SL005221.Q14162.SCARF1 no
SL005222.Q96GP6.SCARF2 no
SL005223.Q6UWB1.IL27RA no
SL005224.P40238.MPL no
SL005225.P04629.NTRK1 no
SL005226.Q9HC73.CRLF2 no
SL005227.Q9BZM6.ULBP1 no
SL005228.Q9BZM5.ULBP2 yes
SL005229.Q9BZM4.ULBP3 no
SL005230.O95185.UNC5C no
SL005231.Q6UXZ4.UNC5D no
SL005233.Q9HAV5.EDA2R no
SL005234.O60383.GDF9 no
SL005235.Q9H9S0.NANOG no
SL005236.P48745.NOV no
SL005250.P23946.CMA1 no
SL005256.P16403.HIST1H1C yes
SL005258.P53350.PLK1 no
SL005261.P17706.PTPN2 no
SL005263.P30533.LRPAP1 yes
SL005266.P37840.SNCA no
SL005308.P61289.PSME3 no
SL005352.Q01469.FABP5 no
SL005357.P05451.REG1A no
SL005358.P30086.PEBP1 yes
SL005361.P05090.APOD no
SL005372.O95219.SNX4 no
SL005392.P15289.ARSA no
SL005403.Q12907.LMAN2 no
SL005430.Q8WVN6.SECTM1 yes
SL005437.Q9NQ76.MEPE no
SL005488.Q14515.SPARCL1 no
SL005491.Q14982.OPCML no
SL005493.P27169.PON1 no
SL005508.Q16790.CA9 no
SL005572.P06396.GSN yes
SL005574.Q03154.ACY1 no
SL005575.P21217.FUT3 no
SL005588.P16591.FER no
SL005629.Q9UJ70.NAGK no
SL005630.P60900.PSMA6 no
SL005675.P06576.ATP5B no
SL005679.P13693.TPT1 no
SL005685.P24534.EEF1B2 no
SL005687.P63241.EIF5A no
SL005688.P63104.YWHAZ no
SL005694.P30041.PRDX6 no
SL005699.O14791.APOL1 no
SL005703.P46531.NOTCH1 no
SL005725.O75791.GRAP2 no
SL005730.O00408.PDE2A no
SL005764.Q86VB7.CD163 no
SL005789.P52823.STC1 no
SL005793.P30405.PPIF no
SL005797.P01833.PIGR no
SL005846.P26038.MSN no
SL006029.Q13231.CHIT1 no
SL006088.Q9NYA1.SPHK1 no
SL006091.P16333.NCK1 no
SL006108.O43866.CD5L no
SL006114.Q01973.ROR1 no
SL006119.Q07654.TFF3 no
SL006131.P07148.FABP1 no
SL006132.P20700.LMNB1 no
SL006189.Q02241.KIF23 no
SL006197.Q96DA6.DNAJC19 no
SL006230.P51884.LUM no
SL006268.Q9UNZ2.NSFL1C no
SL006372.P07947.YES1 no
SL006374.P51813.BMX no
SL006378.P10768.ESD no
SL006397.O14786.NRP1 no
SL006406.O60486.PLXNC1 no
SL006448.P04196.HRG no
SL006460.P07359.GP1BA no
SL006476.P30419.NMT1 no
SL006480.P35030.PRSS3 no
SL006512.Q04756.HGFAC no
SL006522.Q08380.LGALS3BP no
SL006527.Q12805.EFEMP1 no
SL006528.Q12884.FAP no
SL006542.Q15485.FCN2 no
SL006544.Q15582.TGFBI yes
SL006550.Q16610.ECM1 no
SL006610.Q76LX8.ADAMTS13 no
SL006629.Q8IXJ6.SIRT2 no
SL006675.Q8WWK9.CKAP2 no
SL006694.Q96KN2.CNDP1 no
SL006698.Q8N3X6.LCORL no
SL006705.Q99471.PFDN5 yes
SL006713.Q9BWP8.COLEC11 no
SL006777.Q9UGM5.FETUB no
SL006803.Q9Y5C1.ANGPTL3 no
SL006805.Q9Y5S2.CDC42BPB no
SL006830.Q9BXR6.CFHR5 yes
SL006892.P00519.ABL1 no
SL006910.O60911.CTSV no
SL006911.O14757.CHEK1 no
SL006912.P09769.FGR no
SL006913.P06241.FYN no
SL006914.P04150.NR3C1 no
SL006915.Q8NEV9 Q14213.IL27 EBI3 no
SL006916.P06239.LCK no
SL006917.P07948.LYN no
SL006918.P28482.MAPK1 no
SL006919.O75582.RPS6KA5 no
SL006920.Q16539.MAPK14 no
SL006921.Q15118.PDK1 no
SL006922.Q06609.RAD51 no
SL006923.P20226.TBP no
SL006924.O00253.AGRP no
SL006970.O00548.DLL1 no
SL006992.O15232.MATN3 no
SL006993.O15264.MAPK13 no
SL006998.O15530.PDPK1 no
SL007003.O43323.DHH no
SL007022.O60506.SYNCRIP no
SL007024.O60565.GREM1 no
SL007025.O60674.JAK2 no
SL007033.Q8N2S1.LTBP4 no
SL007049.O76096.CST7 no
SL007056.O95393.BMP10 no
SL007059.O95711.LY86 no
SL007070.P01130.LDLR no
SL007100.P09960.LTA4H no
SL007108.P10914.IRF1 no
SL007121.P14091.CTSE no
SL007122.P14735.IDE no
SL007136.P17676.CEBPB no
SL007145.P20393.NR1D1 no
SL007151.P21695.GPD1 no
SL007153.P22079.LPO no
SL007173.P28799.GRN no
SL007179.P29323.EPHB2 no
SL007181.P29597.TYK2 no
SL007195.P32970.CD70 no
SL007206.P35442.THBS2 no
SL007207.P35443.THBS4 yes
SL007217.P38484.IFNGR2 no
SL007221.P40763.STAT3 no
SL007228.P41743.PRKCI no
SL007229.P42226.STAT6 no
SL007237.P45985.MAP2K4 yes
SL007242.P46734.MAP2K3 no
SL007250.P48736.PIK3CG no
SL007261.P50579.METAP2 no
SL007266.P51665.PSMD7 no
SL007272.P52789.HK2 no
SL007274.P52799.EFNB2 no
SL007280.P53634.CTSC no
SL007281.P53778.MAPK12 no
SL007284.P54108.CRISP3 no
SL007295.P55291.CDH15 no
SL007306.P58499.FAM3B no
SL007310.P60763.RAC3 no
SL007311.P60880.SNAP25 no
SL007324.P68400.CSNK2A1 no
SL007327.P78380.OLR1 no
SL007328.P78504.JAG1 no
SL007336.Q01105.SET yes
SL007356.Q04721.NOTCH2 no
SL007358.Q04759.PRKCQ yes
SL007361.Q05315.CLC no
SL007373.Q08752.PPID no
SL007385.Q13007.IL24 no
SL007429.Q14956.GPNMB no
SL007453.Q15759.MAPK11 yes
SL007471.Q5KU26.COLEC12 no
SL007502.Q7LFX5.CHST15 no
SL007531.Q8N8U9.BMPER no
SL007547.Q8TDQ0.HAVCR2 no
SL007560.Q8WWQ8.STAB2 no
SL007620.Q99665.IL12RB2 no
SL007631.Q9BQB4.SOST no
SL007640.Q9BXN2.CLEC7A no
SL007642.Q9BY76.ANGPTL4 no
SL007651.Q9GZV9.FGF23 no
SL007673.Q9HB63.NTN4 no
SL007674.Q9HBG7.LY9 no
SL007680.Q9HCK4.ROBO2 no
SL007696.Q9NPY3.CD93 no
SL007729.Q9NZ08.ERAP1 no
SL007747.Q9UHD2.TBK1 no
SL007752.Q9UIK4.DAPK2 no
SL007756.Q9UK05.GDF2 no
SL007774.Q9Y219.JAG2 no
SL007804.P21810.BGN no
SL007806.Q8N6P7.IL22RA1 no
SL007828.Q8WWG1.NRG4 no
SL007869.P23284.PPIB no
SL007871.P30085.CMPK1 no
SL007888.P01036.CST4 no
SL007953.O00764.PDXK no
SL008023.P10915.HAPLN1 no
SL008039.P14550.AKR1A1 no
SL008059.P23396.RPS3 no
SL008063.P24666.ACP1 no
SL008071.P27348.YWHAQ no
SL008072.P27658.COL8A1 no
SL008085.P31937.HIBADH no
SL008094.P36871.PGM1 no
SL008099.P40121.CAPG no
SL008102.P40925.MDH1 no
SL008113.P48047.ATP5O no
SL008122.P51452.DUSP3 no
SL008143.P61088.UBE2N no
SL008157.P68036.UBE2L3 no
SL008158.P68431.HIST1H3A no
SL008176.Q06323.PSME1 no
SL008177.Q07021.C1QBP no
SL008178.Q07507.DPT yes
SL008190.Q13813.SPTAN1 no
SL008193.Q14112.NID2 no
SL008309.Q9NQC3.RTN4 no
SL008331.Q9UQ80.PA2G4 no
SL008360.O43155.FLRT2 no
SL008372.Q9NZU0.FLRT3 no
SL008378.Q13542.EIF4EBP2 no
SL008380.Q9UBR2.CTSZ no
SL008381.Q9UBX1.CTSF no
SL008382.P28325.CST5 no
SL008402.O95274.LYPD3 no
SL008414.O15197.EPHB6 no
SL008416.Q9UBG0.MRC2 no
SL008421.Q9UHI8.ADAMTS1 no
SL008466.P46952.HAAO no
SL008486.O00182.LGALS9 no
SL008504.P15586.GNS yes
SL008516.P09228.CST2 no
SL008522.Q13591.SEMA5A no
SL008574.Q99983.OMD no
SL008588.Q9UIB8.CD84 no
SL008591.P04155.TFF1 no
SL008609.O75015.FCGR3B no
SL008611.Q02083.NAAA no
SL008614.P98172.EFNB1 no
SL008623.Q02246.CNTN2 no
SL008631.Q02487.DSC2 yes
SL008639.P22304.IDS yes
SL008644.Q10588.BST1 no
SL008703.P16870.CPE no
SL008709.Q14574.DSC3 no
SL008728.Q9HDB5.NRXN3 no
SL008759.Q9HCN6.GP6 no
SL008760.Q96PX8.SLITRK1 no
SL008773.Q6YHK3.CD109 no
SL008808.P63208.SKP1 no
SL008810.Q7Z3B1.NEGR1 no
SL008822.Q9UHX3.ADGRE2 no
SL008835.P07306.ASGR1 no
SL008837.P08962.CD63 no
SL008865.P25787.PSMA2 no
SL008904.Q9Y5Y7.LYVE1 yes
SL008909.Q99538.LGMN no
SL008916.Q9UHL4.DPP7 no
SL008931.Q8N6Q3.CD177 no
SL008933.Q99497.PARK7 no
SL008936.O00533.CHL1 no
SL008945.Q08188.TGM3 no
SL008956.P15848.ARSB no
SL008967.P78324.SIRPA no
SL009045.Q6UWV6.ENPP7 no
SL009054.P58400.NRXN1 no
SL009089.Q96GW7.BCAN no
SL009202.Q86YT9.AMICA1 no
SL009207.Q13561.DCTN2 no
SL009210.P01189.POMC no
SL009213.P10619.CTSA no
SL009216.P20711.DDC no
SL009324.O95633.FSTL3 no
SL009328.P0DML2 P0DML3.CSH1 CSH2 no
SL009341.P35613.BSG no
SL009349.Q12841.FSTL1 no
SL009400.Q9BU40.CHRDL1 yes
SL009412.Q9UBP4.DKK3 no
SL009431.P49773.HINT1 no
SL009628.Q9UK53.ING1 no
SL009629.O95243.MBD4 no
SL009768.P45973.CBX5 no
SL009790.P62306.SNRPF no
SL009791.Q99729.HNRNPAB no
SL009868.Q08945.SSRP1 no
SL009948.O15031.PLXNB2 no
SL009951.O00755.WNT7A no
SL010250.P31948.STIP1 no
SL010288.P23280.CA6 no
SL010328.Q15648.MED1 no
SL010348.P02751.FN1 yes
SL010349.P02751.FN1 yes
SL010368.P35475.IDUA no
SL010369.P22748.CA4 no
SL010371.P49961.ENTPD1 no
SL010372.P98073.TMPRSS15 no
SL010373.P24071.FCAR no
SL010374.P53582.METAP1 no
SL010375.Q9NR71.ASAH2 no
SL010376.Q495T6.MMEL1 no
SL010378.P07949.RET no
SL010379.Q14563.SEMA3A no
SL010381.Q9UK85.DKKL1 no
SL010384.Q08629.SPOCK1 no
SL010388.P07478.PRSS2 no
SL010390.Q76M96.CCDC80 no
SL010391.Q8TEU8.WFIKKN2 no
SL010393.Q8NCW0.KREMEN2 no
SL010449.Q9NS85.CA10 no
SL010450.P09326.CD48 yes
SL010451.P0CG37.CFC1 no
SL010454.Q8IWV2.CNTN4 no
SL010455.O94779.CNTN5 no
SL010456.P01037.CST1 no
SL010457.Q9NR61.DLL4 no
SL010458.Q9NQ30.ESM1 no
SL010459.P12318.FCGR2A no
SL010460.P31994.FCGR2B no
SL010461.P12314.FCGR1A no
SL010462.O00602.FCN1 no
SL010463.Q8N158.GPC2 no
SL010464.Q6UXM1.LRIG3 no
SL010465.O00339.MATN2 no
SL010466.Q9BY79.MFRP no
SL010467.Q96B86.RGMA no
SL010468.Q6NW40.RGMB no
SL010469.Q6ZVN8.HFE2 no
SL010470.O15041.SEMA3E no
SL010471.Q92563.SPOCK2 no
SL010488.P42684.ABL2 no
SL010489.Q14012.CAMK1 no
SL010490.Q8IU85.CAMK1D no
SL010491.Q9UQM7.CAMK2A no
SL010492.Q13554.CAMK2B no
SL010493.Q13557.CAMK2D no
SL010494.P06493 P14635.CDC2 CCNB1 no
SL010495.P24941 P20248.CDK2 CCNA2 yes
SL010496.Q00535 Q15078.CDK5 CDK5R1 no
SL010498.P29320.EPHA3 no
SL010499.P08631.HCK no
SL010500.P07948.LYN no
SL010501.P36507.MAP2K2 no
SL010502.P45983.MAPK8 no
SL010503.P49137.MAPKAPK2 no
SL010504.Q8IW41.MAPKAPK5 no
SL010505.P42679.MATK no
SL010508.O75914.PAK3 no
SL010509.Q9NQU5.PAK6 no
SL010510.Q9P286.PAK7 no
SL010512.P42336 P27986.PIK3CA PIK3R1 no
SL010513.P17612.PRKACA no
SL010514.Q13882.PTK6 no
SL010515.P51812.RPS6KA3 no
SL010516.P12931.SRC no
SL010517.O75716.STK16 no
SL010518.P42680.TEC no
SL010519.P43403.ZAP70 no
SL010520.Q96GD4.AURKB no
SL010521.Q06187.BTK no
SL010522.P49336 P24863.CDK8 CCNC no
SL010523.Q9H422.HIPK3 no
SL010524.Q9BYP7.WNK3 no
SL010528.P61960.UFM1 no
SL010529.Q9Y3C8.UFC1 no
SL010530.Q9NX40.OCIAD1 no
SL010610.Q9UJ71.CD207 no
SL010612.Q9UBT3.DKK4 no
SL010613.Q8NFM7.IL17RD no
SL010616.Q06124.PTPN11 no
SL010617.P20231.TPSB2 no
SL010619.Q9NRR2.TPSG1 no
SL010830.P11171.EPB41 no
SL010927.Q14974.KPNB1 no
SL010928.P12268.IMPDH2 no
SL010973.P25786.PSMA1 no
SL011049.P48740.MASP1 no
SL011068.Q8NAC3.IL17RC no
SL011069.Q9BQR3.PRSS27 no
SL011071.Q9NRA1.PDGFC no
SL011073.Q9NQW7.XPNPEP1 yes
SL011100.Q15762.CD226 no
SL011180.P19367.HK1 no
SL011202.P54920.NAPA no
SL011211.P78344.EIF4G2 no
SL011232.Q16543.CDC37 no
SL011400.P54750.PDE1A no
SL011404.Q08499.PDE4D no
SL011405.O76074.PDE5A no
SL011406.Q13946.PDE7A no
SL011448.P43489.TNFRSF4 no
SL011498.P18509.ADCYAP1 no
SL011499.P01298.PPY no
SL011508.P18509.ADCYAP1 no
SL011509.P10082.PYY no
SL011510.P61278.SST no
SL011528.P62081.RPS7 no
SL011529.Q9Y3A5.SBDS no
SL011530.Q9NP97.DYNLRB1 no
SL011532.O95571.ETHE1 no
SL011535.Q14498.RBM39 no
SL011549.Q99856.ARID3A no
SL011588.P61247.RPS3A no
SL011616.P38919.EIF4A3 no
SL011628.Q9UJU6.DBNL no
SL011629.O00170.AIP no
SL011630.Q6UXD5.SEZ6L2 no
SL011631.Q13765.NACA no
SL011708.P56211.ARPP19 no
SL011709.Q96GD0.PDXP no
SL011768.Q8IVD9.NUDCD3 no
SL011769.Q92688.ANP32B no
SL011770.Q9UIC8.LCMT1 no
SL011772.O00541.PES1 no
SL011808.Q99829.CPNE1 no
SL011809.Q9H773.DCTPP1 no
SL011888.Q9H4F8.SMOC1 no
SL012108.P19174.PLCG1 no
SL012148.P50542.PEX5 no
SL012168.Q9HAP6.LIN7B yes
SL012188.Q9UBC2.EPS15L1 no
SL012248.Q05397.PTK2 no
SL012395.O95631.NTN1 no
SL012457.P58417.NXPH1 yes
SL012469.P78333.GPC5 no
SL012517.Q2I0M5.RSPO4 no
SL012538.Q49AH0.CDNF yes
SL012561.Q9BYZ8.REG4 no
SL012698.Q99706.KIR2DL4 no
SL012707.Q8NBP7.PCSK9 no
SL012740.Q8TE58.ADAMTS15 no
SL012754.Q92484.SMPDL3A no
SL012769.Q96BQ1.FAM3D no
SL012774.Q96HD1.CRELD1 no
SL012783.Q96NZ8.WFIKKN1 no
SL012822.Q9GZN4.PRSS22 no
SL012881.Q9Y625.GPC6 no
SL013165.P05114.HMGN1 no
SL013240.P46108.CRK no
SL013488.Q9P126.CLEC1B no
SL013489.Q9BXJ7.AMN no
SL013490.Q9BWV1.BOC no
SL013548.Q6ZMJ4.IL34 no
SL013570.O43781.DYRK3 no
SL013754.P20936.RASA1 no
SL013872.Q9NZR2.LRP1B no
SL013928.Q9UNP9.PPIE no
SL013969.Q16719.KYNU no
SL013988.Q9Y4C5.CHST2 no
SL013989.Q6UXX9.RSPO2 no
SL014008.Q11128.FUT5 no
SL014009.Q7Z4V5.HDGFRP2 no
SL014028.O75356.ENTPD5 no
SL014029.Q9NRA0.SPHK2 no
SL014048.Q86Y22.COL23A1 no
SL014069.Q16549.PCSK7 no
SL014070.O94991.SLITRK5 no
SL014071.Q9NZU1.FLRT1 no
SL014088.Q96P31.FCRL3 no
SL014091.Q96PQ0.SORCS2 no
SL014092.Q4KMG0.CDON no
SL014093.O75355.ENTPD3 no
SL014094.Q8IZF4.ADGRG5 no
SL014096.Q86UE6.LRRTM1 no
SL014108.Q86VH5.LRRTM3 no
SL014111.Q8IZU9.KIRREL3 no
SL014113.Q8N0W4.NLGN4X no
SL014129.O60243.HS6ST1 no
SL014130.Q9GZX3.CHST6 no
SL014148.Q96MS0.ROBO3 no
SL014188.Q9BZW8.CD244 no
SL014208.O95727.CRTAM no
SL014209.Q9NZS2.KLRF1 no
SL014228.Q96DU3.SLAMF6 no
SL014229.Q01151.CD83 no
SL014248.Q9H3T3.SEMA6B no
SL014268.P41217.CD200 no
SL014269.P43630.KIR3DL2 no
SL014270.Q08708.CD300C no
SL014288.Q8TD46.CD200R1 no
SL014289.Q14943.KIR3DS1 no
SL014292.Q08ET2.SIGLEC14 no
SL014294.Q5JZY3.EPHA10 no
SL014308.P55075.FGF8 no
SL014468.O60880.SH2D1A no
SL014469.P29353.SHC1 no
SL014470.O75815.BCAR3 no
SL014488.P15498.VAV1 no
SL014684.P00973.OAS1 no
SL014735.P20839.IMPDH1 yes
SL014896.Q01484.ANK2 no
SL014983.Q16778.HIST2H2BE no
SL015046.Q86SJ2.AMIGO2 no
SL015510.P05161.ISG15 no
SL015728.Q14397.GCKR no
SL016128.O95881.TXNDC12 no
SL016129.Q9H098.FAM107B no
SL016130.Q92994.BRF1 no
SL016148.Q70626.Human-virus no
SL016548.Q13131 Q9Y478 P54619.PRKAA1 PRKAB1 PRKAG1 yes
SL016549.P54646 O43741 P54619.PRKAA2 PRKAB2 PRKAG1 no
SL016550.P68400 P67870.CSNK2A1 CSNK2B no
SL016551.P19784 P67870.CSNK2A2 CSNK2B no
SL016553.Q14432.PDE3A no
SL016554.O76083.PDE9A no
SL016555.Q9HCR9.PDE11A no
SL016557.P04035.HMGCR no
SL016563.Q9H1K4.SLC25A18 no
SL016566.O94768.STK17B no
SL016567.O43318 Q15750.MAP3K7 TAB1 no
SL016828.P00533.EGFR no
SL016928.Q9NQ25.SLAMF7 no
SL016969.P50461.CSRP3 no
SL017106.P01566.IFNA10 no
SL017128.Q5S007.LRRK2 no
SL017188.P49840 P49841.GSK3A GSK3B no
SL017189.P01042.KNG1 no
SL017289.P0CG47.UBB no
SL017290.P0CG48.UBC no
SL017328.Q00872.MYBPC1 no
SL017424.Q9H7M9.C10orf54 no
SL017528.O60930.RNASEH1 no
SL017529.Q14145.KEAP1 no
SL017610.P19876 P19875.CXCL3 CXCL2 no
SL017611.P31946, P62258, P61981, Q04917, P27348, P63104, P31947.YWHAB,YWHAE,YWHAG,YWHAH,YWHAQ,YWHAZ,SFN no
SL017612.P07900 P08238.HSP90AA1 HSP90AB1 no
SL017614.P31749 P31751 Q9Y243.AKT1 AKT2 AKT3 no
SL018256.Q9Y259.CHKB no
SL018509.Q9BXY4.RSPO3 no
SL018548.P01011.SERPINA3 no
SL018587.Q6UXK2.ISLR2 no
SL018625.O00206 Q9Y6Y9.TLR4 LY96 no
SL018629.Q68DV7.RNF43 no
SL018891.O60469.DSCAM no
SL018921.Q9Y5N5.N6AMT1 no
SL018938.P55854.SUMO3 no
SL018946.P60604.UBE2G2 no
SL018947.Q9UHP3.USP25 no
SL018971.Q9ULT6.ZNRF3 no
SL019019.Q8IYJ0.PIANP no
SL019096.Q8N2W9.PIAS4 yes
SL019100.Q9UNE7.STUB1 no
SL019978.P01567.IFNA7 no
SL019979.Q7L7L0.HIST3H2A no
SL020171.Q9UM44.HHLA2 no
SL020172.Q9HBX9.RXFP1 no
SL021043.O95390 O14793.GDF11 MSTN no
ENC_sex_is_Female no
ENC_sex_is_Male no

Interpretation/Literature Search

The following links can help with hypothesis generation. Names of variables likely need modification.

important_features url
SL004783.P80511.S100A12 https://pubmed.ncbi.nlm.nih.gov/?term=SL004783.P80511.S100A12%20AND%20grade
SL004867.P07451.CA3 https://pubmed.ncbi.nlm.nih.gov/?term=SL004867.P07451.CA3%20AND%20grade
SL007207.P35443.THBS4 https://pubmed.ncbi.nlm.nih.gov/?term=SL007207.P35443.THBS4%20AND%20grade
SL007453.Q15759.MAPK11 https://pubmed.ncbi.nlm.nih.gov/?term=SL007453.Q15759.MAPK11%20AND%20grade
SL000310.P00736.C1R https://pubmed.ncbi.nlm.nih.gov/?term=SL000310.P00736.C1R%20AND%20grade
SL004557.P13987.CD59 https://pubmed.ncbi.nlm.nih.gov/?term=SL004557.P13987.CD59%20AND%20grade
SL008178.Q07507.DPT https://pubmed.ncbi.nlm.nih.gov/?term=SL008178.Q07507.DPT%20AND%20grade
SL008904.Q9Y5Y7.LYVE1 https://pubmed.ncbi.nlm.nih.gov/?term=SL008904.Q9Y5Y7.LYVE1%20AND%20grade
SL006544.Q15582.TGFBI https://pubmed.ncbi.nlm.nih.gov/?term=SL006544.Q15582.TGFBI%20AND%20grade
SL001796.P05164.MPO https://pubmed.ncbi.nlm.nih.gov/?term=SL001796.P05164.MPO%20AND%20grade
SL004359.P20783.NTF3 https://pubmed.ncbi.nlm.nih.gov/?term=SL004359.P20783.NTF3%20AND%20grade
SL006705.Q99471.PFDN5 https://pubmed.ncbi.nlm.nih.gov/?term=SL006705.Q99471.PFDN5%20AND%20grade
SL003187.O00626.CCL22 https://pubmed.ncbi.nlm.nih.gov/?term=SL003187.O00626.CCL22%20AND%20grade
SL003197.O15444.CCL25 https://pubmed.ncbi.nlm.nih.gov/?term=SL003197.O15444.CCL25%20AND%20grade
SL001777.P01034.CST3 https://pubmed.ncbi.nlm.nih.gov/?term=SL001777.P01034.CST3%20AND%20grade
SL006830.Q9BXR6.CFHR5 https://pubmed.ncbi.nlm.nih.gov/?term=SL006830.Q9BXR6.CFHR5%20AND%20grade
SL005572.P06396.GSN https://pubmed.ncbi.nlm.nih.gov/?term=SL005572.P06396.GSN%20AND%20grade
SL000460.P01880.IGHD IGK@ IGL@ https://pubmed.ncbi.nlm.nih.gov/?term=SL000460.P01880.IGHD%20%20IGK%40%20IGL%40%20AND%20grade
SL000027.P35354.PTGS2 https://pubmed.ncbi.nlm.nih.gov/?term=SL000027.P35354.PTGS2%20AND%20grade
SL000441.P14210.HGF https://pubmed.ncbi.nlm.nih.gov/?term=SL000441.P14210.HGF%20AND%20grade
SL010348.P02751.FN1 https://pubmed.ncbi.nlm.nih.gov/?term=SL010348.P02751.FN1%20AND%20grade
SL002621.P21741.MDK https://pubmed.ncbi.nlm.nih.gov/?term=SL002621.P21741.MDK%20AND%20grade
SL004180.P28908.TNFRSF8 https://pubmed.ncbi.nlm.nih.gov/?term=SL004180.P28908.TNFRSF8%20AND%20grade
SL000408.P01588.EPO https://pubmed.ncbi.nlm.nih.gov/?term=SL000408.P01588.EPO%20AND%20grade
SL004120.Q16832.DDR2 https://pubmed.ncbi.nlm.nih.gov/?term=SL004120.Q16832.DDR2%20AND%20grade
SL014735.P20839.IMPDH1 https://pubmed.ncbi.nlm.nih.gov/?term=SL014735.P20839.IMPDH1%20AND%20grade
SL004672.Q02223.TNFRSF17 https://pubmed.ncbi.nlm.nih.gov/?term=SL004672.Q02223.TNFRSF17%20AND%20grade
SL005263.P30533.LRPAP1 https://pubmed.ncbi.nlm.nih.gov/?term=SL005263.P30533.LRPAP1%20AND%20grade
SL004489.O00206.TLR4 https://pubmed.ncbi.nlm.nih.gov/?term=SL004489.O00206.TLR4%20AND%20grade
SL001938.P08476.INHBA https://pubmed.ncbi.nlm.nih.gov/?term=SL001938.P08476.INHBA%20AND%20grade
SL005358.P30086.PEBP1 https://pubmed.ncbi.nlm.nih.gov/?term=SL005358.P30086.PEBP1%20AND%20grade
SL004843.O43921.EFNA2 https://pubmed.ncbi.nlm.nih.gov/?term=SL004843.O43921.EFNA2%20AND%20grade
SL004296.P00568.AK1 https://pubmed.ncbi.nlm.nih.gov/?term=SL004296.P00568.AK1%20AND%20grade
SL007336.Q01105.SET https://pubmed.ncbi.nlm.nih.gov/?term=SL007336.Q01105.SET%20AND%20grade
SL012457.P58417.NXPH1 https://pubmed.ncbi.nlm.nih.gov/?term=SL012457.P58417.NXPH1%20AND%20grade
SL000022.P02671 P02675 P02679.FGA FGB FGG https://pubmed.ncbi.nlm.nih.gov/?term=SL000022.P02671%20P02675%20P02679.FGA%20FGB%20FGG%20AND%20grade
SL004363.Q9Y240.CLEC11A https://pubmed.ncbi.nlm.nih.gov/?term=SL004363.Q9Y240.CLEC11A%20AND%20grade
SL000164.P02144.MB https://pubmed.ncbi.nlm.nih.gov/?term=SL000164.P02144.MB%20AND%20grade
SL005430.Q8WVN6.SECTM1 https://pubmed.ncbi.nlm.nih.gov/?term=SL005430.Q8WVN6.SECTM1%20AND%20grade
SL000836.P69905, P68871.HBA1 HBB https://pubmed.ncbi.nlm.nih.gov/?term=SL000836.P69905%2C%20P68871.HBA1%20HBB%20AND%20grade
SL000403.P39060.COL18A1 https://pubmed.ncbi.nlm.nih.gov/?term=SL000403.P39060.COL18A1%20AND%20grade
SL007358.Q04759.PRKCQ https://pubmed.ncbi.nlm.nih.gov/?term=SL007358.Q04759.PRKCQ%20AND%20grade
SL012538.Q49AH0.CDNF https://pubmed.ncbi.nlm.nih.gov/?term=SL012538.Q49AH0.CDNF%20AND%20grade
SL010450.P09326.CD48 https://pubmed.ncbi.nlm.nih.gov/?term=SL010450.P09326.CD48%20AND%20grade
SL010349.P02751.FN1 https://pubmed.ncbi.nlm.nih.gov/?term=SL010349.P02751.FN1%20AND%20grade
SL008631.Q02487.DSC2 https://pubmed.ncbi.nlm.nih.gov/?term=SL008631.Q02487.DSC2%20AND%20grade
SL005256.P16403.HIST1H1C https://pubmed.ncbi.nlm.nih.gov/?term=SL005256.P16403.HIST1H1C%20AND%20grade
SL002704.P21246.PTN https://pubmed.ncbi.nlm.nih.gov/?term=SL002704.P21246.PTN%20AND%20grade
SL004858.P56159.GFRA1 https://pubmed.ncbi.nlm.nih.gov/?term=SL004858.P56159.GFRA1%20AND%20grade
SL003770.Q8N474.SFRP1 https://pubmed.ncbi.nlm.nih.gov/?term=SL003770.Q8N474.SFRP1%20AND%20grade
SL012168.Q9HAP6.LIN7B https://pubmed.ncbi.nlm.nih.gov/?term=SL012168.Q9HAP6.LIN7B%20AND%20grade
SL003733.Q9NR28.DIABLO https://pubmed.ncbi.nlm.nih.gov/?term=SL003733.Q9NR28.DIABLO%20AND%20grade
SL004008.P24158.PRTN3 https://pubmed.ncbi.nlm.nih.gov/?term=SL004008.P24158.PRTN3%20AND%20grade
SL004939.P18031.PTPN1 https://pubmed.ncbi.nlm.nih.gov/?term=SL004939.P18031.PTPN1%20AND%20grade
SL004351.Q9H293.IL25 https://pubmed.ncbi.nlm.nih.gov/?term=SL004351.Q9H293.IL25%20AND%20grade
SL000645.P09238.MMP10 https://pubmed.ncbi.nlm.nih.gov/?term=SL000645.P09238.MMP10%20AND%20grade
SL009400.Q9BU40.CHRDL1 https://pubmed.ncbi.nlm.nih.gov/?term=SL009400.Q9BU40.CHRDL1%20AND%20grade
SL019096.Q8N2W9.PIAS4 https://pubmed.ncbi.nlm.nih.gov/?term=SL019096.Q8N2W9.PIAS4%20AND%20grade
SL000485.P15248.IL9 https://pubmed.ncbi.nlm.nih.gov/?term=SL000485.P15248.IL9%20AND%20grade
SL011073.Q9NQW7.XPNPEP1 https://pubmed.ncbi.nlm.nih.gov/?term=SL011073.Q9NQW7.XPNPEP1%20AND%20grade
SL003738.P33681.CD80 https://pubmed.ncbi.nlm.nih.gov/?term=SL003738.P33681.CD80%20AND%20grade
SL008639.P22304.IDS https://pubmed.ncbi.nlm.nih.gov/?term=SL008639.P22304.IDS%20AND%20grade
SL000498.P41159.LEP https://pubmed.ncbi.nlm.nih.gov/?term=SL000498.P41159.LEP%20AND%20grade
SL000306.P16860.NPPB https://pubmed.ncbi.nlm.nih.gov/?term=SL000306.P16860.NPPB%20AND%20grade
SL003672.P08294.SOD3 https://pubmed.ncbi.nlm.nih.gov/?term=SL003672.P08294.SOD3%20AND%20grade
SL000426.P02751.FN1 https://pubmed.ncbi.nlm.nih.gov/?term=SL000426.P02751.FN1%20AND%20grade
SL000525.P09237.MMP7 https://pubmed.ncbi.nlm.nih.gov/?term=SL000525.P09237.MMP7%20AND%20grade
SL000461.P01854.IGHE IGK@ IGL@ https://pubmed.ncbi.nlm.nih.gov/?term=SL000461.P01854.IGHE%20IGK%40%20IGL%40%20AND%20grade
SL005228.Q9BZM5.ULBP2 https://pubmed.ncbi.nlm.nih.gov/?term=SL005228.Q9BZM5.ULBP2%20AND%20grade
SL000087.P05231.IL6 https://pubmed.ncbi.nlm.nih.gov/?term=SL000087.P05231.IL6%20AND%20grade
SL004342.P55075.FGF8 https://pubmed.ncbi.nlm.nih.gov/?term=SL004342.P55075.FGF8%20AND%20grade
SL008504.P15586.GNS https://pubmed.ncbi.nlm.nih.gov/?term=SL008504.P15586.GNS%20AND%20grade
SL010495.P24941 P20248.CDK2 CCNA2 https://pubmed.ncbi.nlm.nih.gov/?term=SL010495.P24941%20P20248.CDK2%20CCNA2%20AND%20grade
SL000524.P08254.MMP3 https://pubmed.ncbi.nlm.nih.gov/?term=SL000524.P08254.MMP3%20AND%20grade
SL007237.P45985.MAP2K4 https://pubmed.ncbi.nlm.nih.gov/?term=SL007237.P45985.MAP2K4%20AND%20grade
SL016548.Q13131 Q9Y478 P54619.PRKAA1 PRKAB1 PRKAG1 https://pubmed.ncbi.nlm.nih.gov/?term=SL016548.Q13131%20Q9Y478%20P54619.PRKAA1%20PRKAB1%20%20PRKAG1%20AND%20grade
SL004140.P52798.EFNA4 https://pubmed.ncbi.nlm.nih.gov/?term=SL004140.P52798.EFNA4%20AND%20grade
SL004742.P43652.AFM https://pubmed.ncbi.nlm.nih.gov/?term=SL004742.P43652.AFM%20AND%20grade
SL002542.P01116.KRAS https://pubmed.ncbi.nlm.nih.gov/?term=SL002542.P01116.KRAS%20AND%20grade
SL000057.P04183.TK1 https://pubmed.ncbi.nlm.nih.gov/?term=SL000057.P04183.TK1%20AND%20grade
SL004438.Q15828.CST6 https://pubmed.ncbi.nlm.nih.gov/?term=SL004438.Q15828.CST6%20AND%20grade

Log


Binary encoded columns created for categorical input variables:

 ->  sex: ['ENC_sex_is_Female', 'ENC_sex_is_Male']

Numeric mapping was created for categorical outcome variable, grade, (sorted alphabetically and factorized):
metastatic maps to 0
pdac maps to 1

*** Percent variation explained is not optimal for categorical outcome variables. 
*** Use caution with interpretation.

BorutaSHAP Figures

⇨ Open PDF in new window


First Delta Dataset


⇨ Open File Directory

Results

Model Summary

Data First
Model Type (Pass/Fail) Not performed
% Variance Explained NA
N Trees NA
Feature fraction/split NA
Max Depth NA
MERF Iters. NA
BorutaSHAP Trials NA
BorutaSHAP Threshold NA
P-value NA
N Study IDs NA
N Samples NA
Input Features NA
Accepted Features NA
Tentative Features NA
Rejected Features NA

Selected Features

important_features decoded_features feature_importance_vals
no_selected_features NA -100

Feature Stats

Analysis not completed

Input Features

Analysis not completed

Interpretation/Literature Search

The following links can help with hypothesis generation. Names of variables likely need modification.

important_features url
no_selected_features https://pubmed.ncbi.nlm.nih.gov/?term=no_selected_features%20AND%20grade

Log

BorutaSHAP Figures

⇨ Open PDF in new window


Previous Delta Dataset


⇨ Open File Directory

Model Summary

Data Previous
Model Type (Pass/Fail) Not performed
% Variance Explained NA
N Trees NA
Feature fraction/split NA
Max Depth NA
MERF Iters. NA
BorutaSHAP Trials NA
BorutaSHAP Threshold NA
P-value NA
N Study IDs NA
N Samples NA
Input Features NA
Accepted Features NA
Tentative Features NA
Rejected Features NA

Selected Features

important_features decoded_features feature_importance_vals
no_selected_features NA -100

Feature Stats

Analysis not completed

Input Features

Analysis not completed

Interpretation/Literature Search

The following links can help with hypothesis generation. Names of variables likely need modification.

important_features url
no_selected_features https://pubmed.ncbi.nlm.nih.gov/?term=no_selected_features%20AND%20grade

Log

BorutaSHAP Figures

⇨ Open PDF in new window


Pairwise Delta Dataset


⇨ Open File Directory

Model Summary

Data Pairwise
Model Type (Pass/Fail) Not performed
% Variance Explained NA
N Trees NA
Feature fraction/split NA
Max Depth NA
MERF Iters. NA
BorutaSHAP Trials NA
BorutaSHAP Threshold NA
P-value NA
N Study IDs NA
N Samples NA
Input Features NA
Accepted Features NA
Tentative Features NA
Rejected Features NA

Selected Features

important_features decoded_features feature_importance_vals
no_selected_features NA -100

Feature Stats

Analysis not completed

Input Features

Analysis not completed

Interpretation/Literature Search

The following links can help with hypothesis generation. Names of variables likely need modification.

important_features url
no_selected_features https://pubmed.ncbi.nlm.nih.gov/?term=no_selected_features%20AND%20grade

Log

BorutaSHAP Figures

⇨ Open PDF in new window


See the Github repository for more information.